Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 12/20 | 0.39 |
| ▸ | TNFSF11 | O14788 | 2/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19971401 | 0.93 | HTR6 (0.39) | ALKHTR6 | |
| SCHEMBL19971356 | 0.91 | IDE (0.37) | ALKP2RX7PDE4APDE4BPDE4C | |
| SCHEMBL16626603 | 0.85 | HTR6 (0.45) | ALKHTR6TNFSF11 | |
| Hydrochloric Acid SCHEMBL16618833 | 0.84 | HTR6 (0.44) | ALKHTR6TNFSF11 | |
| SCHEMBL16618951 | 0.84 | HTR6 (0.46) | ALKHTR6TNFSF11 | |
| SCHEMBL16626614 | 0.81 | HTR6 (0.41) | ALKHTR6TNFSF11 | |
| SCHEMBL16626742 | 0.80 | HTR6 (0.42) | ALKHTR6TNFSF11PDE4APDE4B | |
| Hydrochloric Acid SCHEMBL16618770 | 0.80 | HTR6 (0.41) | ALKHTR6TNFSF11PDE4APDE4B | |
| SCHEMBL16626773 | 0.80 | HTR6 (0.43) | ALKHTR6PDE4APDE4BPDE4C | |
| SCHEMBL19971361 | 0.80 | HTR6 (0.36) | HTR6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |