Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.77 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.77 |
| ▸ | MAOA | P21397 | 2/20 | 0.77 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 3/20 | 0.54 |
| ▸ | CA2 | P00918 | 3/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA7 | P43166 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzocaine SCHEMBL1235972 | 0.88 | LMNA (1.00) | LMNACYP1A2CYP3A4MAOATSHR | |
| Benzocaine SCHEMBL25100 | 0.88 | LMNA (1.00) | LMNACYP1A2CYP3A4MAOATSHR | |
| Benzocaine SCHEMBL19031788 | 0.86 | LMNA (0.96) | LMNACYP1A2CYP3A4MAOATSHR | |
| Benzocaine SCHEMBL944986 | 0.86 | LMNA (0.96) | LMNACYP1A2CYP3A4MAOATSHR | |
| Benzocaine SCHEMBL11021778 | 0.86 | LMNA (0.96) | LMNACYP1A2CYP3A4MAOATSHR | |
| Benzocaine SCHEMBL15200678 | 0.86 | LMNA (0.96) | LMNACYP1A2CYP3A4MAOATSHR | |
| Benzocaine SCHEMBL27914401 | 0.86 | LMNA (0.96) | LMNACYP1A2CYP3A4MAOATSHR | |
| Benzocaine SCHEMBL2389408 | 0.84 | LMNA (0.92) | LMNACYP1A2CYP3A4MAOATSHR | |
| Benzocaine SCHEMBL29029466 | 0.84 | LMNA (0.92) | LMNACYP1A2CYP3A4MAOATSHR | |
| SCHEMBL8726454 | 0.83 | LMNA (0.83) | LMNACYP1A2CYP3A4MAOATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11292760-B2 | Therapeutic acrylates as enhanced medical adhesives | CARNEGIE MELLON UNIVERSITY (US) | 2022-04-05 | — | — | US | disclosed |
| US-20190262497-A1 | Therapeutic Acrylates as Enhanced Medical Adhesives | CARNEGIE MELLON UNIVERSITY | 2019-08-29 | — | — | US | disclosed |
| WO-2018052936-A1 | THERAPEUTIC ACRYLATES AS ENHANCED MEDICAL ADHESIVES | CARNEGIE MELLON UNIVERSITY (US) | 2018-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11292760-B2 | Therapeutic acrylates as enhanced medical adhesives | ILK, COL2A1, BMP2 | LMNA 1083/4885CYP1A2 4767/4885CYP3A4 4738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.