Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | SCN1A | P35498 | 1/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976943 | 0.91 | KMT2A (0.48) | LMNAESR1MEN1KMT2AALDH1A1 | |
| SCHEMBL19976969 | 0.89 | ALDH1A1 (0.49) | LMNAESR1MEN1KMT2AALDH1A1 | |
| SCHEMBL19976930 | 0.87 | ALDH1A1 (0.55) | LMNAMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL19976950 | 0.86 | ALDH1A1 (0.51) | LMNAESR1MEN1KMT2AALDH1A1 | |
| SCHEMBL19976994 | 0.85 | PGR (0.57) | LMNAMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL19976968 | 0.85 | KCNMA1 (0.57) | LMNAMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL19977047 | 0.84 | MRGPRX1 (0.45) | LMNAMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL16999570 | 0.82 | CTSL (0.52) | MEN1KMT2AALDH1A1 | |
| SCHEMBL18261144 | 0.82 | CTSL (0.52) | MEN1KMT2AALDH1A1 | |
| SCHEMBL19976913 | 0.81 | LMNA (0.43) | LMNAESR1KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3102193-B1 | ANTIBACTERIAL AGENTS: N(ALPHA)-AROYL-N-ARYL-PHENYLALANINAMIDES | UNIV RUTGERS (US) | 2023-01-11 | — | — | EP | disclosed |
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |