Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.47 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976980 | 0.87 | NPC1 (0.66) | MEN1KMT2AMAPTHTTNPC1 | |
| SCHEMBL19977009 | 0.86 | KMT2A (0.53) | MEN1KMT2AMAPTHTTNPC1 | |
| SCHEMBL19976930 | 0.85 | ALDH1A1 (0.55) | MEN1KMT2AMAPTHTTCRHBP | |
| SCHEMBL19976950 | 0.84 | ALDH1A1 (0.51) | MEN1KMT2AMAPTHTTNPC1 | |
| SCHEMBL16993955 | 0.83 | PSMB5 (0.55) | HDAC1HDAC8HDAC6ALDH1A1GPR139 | |
| SCHEMBL19977059 | 0.82 | KMT2A (0.58) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL19976970 | 0.81 | NPC1 (0.53) | MEN1KMT2AMAPTHTTNPC1 | |
| SCHEMBL16999801 | 0.80 | CTSL (0.54) | HDAC1HDAC8HDAC6ALDH1A1 | |
| SCHEMBL18261135 | 0.80 | CTSL (0.54) | HDAC1HDAC8HDAC6ALDH1A1 | |
| SCHEMBL19976935 | 0.77 | TUBB4A (0.47) | MEN1KMT2AMAPTHTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |