Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 1/20 | 0.48 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | SCN1A | P35498 | 1/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.44 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976957 | 0.91 | PGR (0.44) | KCNK3KCNK9POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL19977069 | 0.89 | ALDH1A1 (0.57) | KCNK3KCNK9POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL19976955 | 0.85 | POLB (0.53) | POLBALDH1A1SMN1; SMN2PGRSCN1A | |
| SCHEMBL19977138 | 0.83 | HPGD (0.48) | KCNK3KCNK9POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL19977018 | 0.83 | SMN1; SMN2 (0.50) | POLBALDH1A1SMN1; SMN2HPGDRAB9A | |
| SCHEMBL19977072 | 0.83 | LMNA (0.54) | KCNK3KCNK9POLBSMN1; SMN2HPGD | |
| SCHEMBL16999515 | 0.83 | USP30 (0.57) | L3MBTL1 | |
| SCHEMBL19976970 | 0.81 | NPC1 (0.53) | KCNK3KCNK9ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL19977071 | 0.81 | LMNA (0.45) | POLBALDH1A1SMN1; SMN2HPGDRAB9A | |
| SCHEMBL19976922 | 0.81 | HPGD (0.66) | POLBALDH1A1SMN1; SMN2PGRSCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |