Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19977071 | 0.90 | LMNA (0.45) | LMNAKMT2ASMN1; SMN2POLBHTT | |
| SCHEMBL19976955 | 0.86 | POLB (0.53) | LMNASMN1; SMN2POLBGAAHTT | |
| SCHEMBL10211579 | 0.86 | KMT2A (0.67) | LMNAKMT2APOLBGAAHTT | |
| SCHEMBL19977018 | 0.84 | SMN1; SMN2 (0.50) | LMNAKMT2ASMN1; SMN2POLBGAA | |
| SCHEMBL16999513 | 0.83 | USP30 (0.58) | — | |
| SCHEMBL19977070 | 0.83 | KCNK3 (0.48) | LMNASMN1; SMN2POLBGAAHPGD | |
| SCHEMBL19976970 | 0.82 | NPC1 (0.53) | LMNAKMT2ASMN1; SMN2HTTHPGD | |
| SCHEMBL19976922 | 0.82 | HPGD (0.66) | LMNASMN1; SMN2POLBGAAHTT | |
| SCHEMBL19976977 | 0.81 | SMN1; SMN2 (0.48) | LMNAKMT2ASMN1; SMN2POLBHPGD | |
| SCHEMBL19976979 | 0.81 | TAS2R14 (0.50) | LMNASMN1; SMN2POLBKCNK3KCNK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |