Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PYGL | P06737 | 1/20 | 0.41 |
| ▸ | CCKAR | P32238 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976949 | 0.88 | KMT2A (0.45) | LMNAMEN1KMT2ACCKARKEAP1 | |
| SCHEMBL19977033 | 0.88 | TRPV1 (0.45) | KMT2APYGLCCKARKEAP1PGR | |
| SCHEMBL19976902 | 0.85 | SMN1; SMN2 (0.45) | PARP1LMNAMEN1KMT2ACCKAR | |
| SCHEMBL16994027 | 0.83 | CTSV (0.48) | MEN1KMT2APYGLCCKAR | |
| SCHEMBL19976994 | 0.81 | PGR (0.57) | LMNAMEN1ALOX12KMT2ANPSR1 | |
| SCHEMBL19976997 | 0.80 | MAPT (0.41) | PARP1LMNAMEN1ALOX12KMT2A | |
| SCHEMBL19976903 | 0.79 | MEN1 (0.50) | PARP1MEN1KMT2ANPSR1PGR | |
| SCHEMBL19977084 | 0.77 | DHPS (0.46) | PARP1LMNAMEN1ALOX12KMT2A | |
| SCHEMBL19976940 | 0.76 | TRPV1 (0.55) | LMNAMEN1KMT2AHTTMAPT | |
| SCHEMBL19977032 | 0.75 | MAPT (0.55) | MEN1ALOX12KMT2ANPSR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |