Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 5/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | GPR6 | P46095 | 3/20 | 0.39 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | GOT1 | P17174 | 4/20 | 0.37 |
| ▸ | DHPS | P49366 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19977014 | 0.88 | ADRB1 (0.49) | BACE1ADRB1HTR6GOT1DHPS | |
| SCHEMBL16999555 | 0.85 | BACE1 (0.46) | BACE1ADRB1HTR6 | |
| SCHEMBL19977012 | 0.85 | ALDH1A1 (0.46) | BACE1GPR6BRPF1 | |
| SCHEMBL19977130 | 0.84 | L3MBTL1 (0.44) | BACE1ADRB1GPR6BRPF1CHEK1 | |
| SCHEMBL19977110 | 0.83 | BACE1 (0.48) | BACE1HTR6BRPF1CHEK1 | |
| SCHEMBL19976913 | 0.82 | LMNA (0.43) | DHPS | |
| SCHEMBL19976987 | 0.81 | ALDH1A1 (0.45) | BACE1BRPF1 | |
| SCHEMBL19976935 | 0.80 | TUBB4A (0.47) | DHPS | |
| SCHEMBL23594204 | 0.78 | SMN1; SMN2 (0.45) | BACE1GPR6BRPF1 | |
| SCHEMBL19976936 | 0.78 | SRPK1 (0.48) | CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |