Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | DHPS | P49366 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.39 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.39 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.39 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.39 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.39 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.39 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.39 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.39 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19977028 | 0.88 | LMNA (0.47) | LMNAKMT2AATMDHPSALDH1A1 | |
| SCHEMBL19976935 | 0.87 | TUBB4A (0.47) | KMT2ADHPSALDH1A1MAPTPYGL | |
| SCHEMBL19977084 | 0.86 | DHPS (0.46) | LMNAKMT2ADHPSALDH1A1MAPT | |
| SCHEMBL16999334 | 0.84 | HPGDS (0.44) | ALDH1A1KDM4EPSMB5PKM | |
| SCHEMBL16994006 | 0.84 | HPGDS (0.44) | ALDH1A1KDM4EPSMB5PKM | |
| SCHEMBL19977064 | 0.82 | BACE1 (0.44) | DHPS | |
| SCHEMBL19976919 | 0.81 | LMNA (0.47) | LMNAESR1KMT2AALDH1A1MAPT | |
| SCHEMBL19976943 | 0.80 | KMT2A (0.48) | LMNAESR1KMT2AALDH1A1MAPT | |
| SCHEMBL24862888 | 0.79 | KMT2A (0.39) | LMNAESR1KMT2AATMDHPS | |
| SCHEMBL19976905 | 0.79 | KMT2A (0.56) | KMT2ADHPSALDH1A1MAPTTUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |