Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.45 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.45 |
| ▸ | XIAP | P98170 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16999648 | 0.81 | USP30 (0.57) | USP30 | |
| SCHEMBL19977087 | 0.81 | SMN1; SMN2 (0.50) | SMN1; SMN2HSPA5HSPA9LMNAGFER | |
| SCHEMBL19976938 | 0.79 | SMN1; SMN2 (0.51) | SMN1; SMN2HSPA5HSPA9LMNAGFER | |
| SCHEMBL19977141 | 0.78 | DHPS (0.56) | SMN1; SMN2USP30NPC1CYP1A2CYP3A4 | |
| SCHEMBL19976922 | 0.76 | HPGD (0.66) | SMN1; SMN2LMNAGFERNPC1CYP1A2 | |
| SCHEMBL19977097 | 0.76 | CYP2C19 (0.48) | SMN1; SMN2LMNAGFERUSP30NPC1 | |
| SCHEMBL19976955 | 0.76 | POLB (0.53) | SMN1; SMN2LMNANPC1CYP1A2CYP3A4 | |
| SCHEMBL19977124 | 0.75 | SMN1; SMN2 (0.62) | SMN1; SMN2LMNANPC1RAB9AMEN1 | |
| SCHEMBL19976894 | 0.75 | ALDH1A1 (0.62) | SMN1; SMN2LMNACYP1A2CYP3A4MEN1 | |
| SCHEMBL19977069 | 0.74 | ALDH1A1 (0.57) | SMN1; SMN2LMNACYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |