Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | HTR2C | P28335 | 3/20 | 0.42 |
| ▸ | HTR2B | P41595 | 3/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 3/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 3/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | SI | P14410 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22623758 | 0.79 | HTR2A (0.42) | SLC6A2SLC6A4CYP2D6KCNH2HTR2A | |
| SCHEMBL9006921 | 0.77 | KIF11 (0.45) | HTR2AHTR2CHTR2BGPR84FFAR1 | |
| SCHEMBL20078216 | 0.77 | HTR2A (0.35) | SLC6A2SLC6A4HTR2AHTR2CHTR2B | |
| SCHEMBL18853764 | 0.76 | HTR2A (0.45) | SLC6A2SLC6A4HTR2AHTR2CHTR2B | |
| SCHEMBL20695516 | 0.76 | HTR2A (0.38) | SLC6A2SLC6A4CYP2D6HTR2AHTR2C | |
| SCHEMBL888682 | 0.72 | KIF11 (0.49) | SLC6A2SLC6A4CYP2D6KCNH2HTR2A | |
| SCHEMBL23978973 | 0.72 | ESR1 (0.47) | SLC6A2CYP2D6HTR2AHTR2BNR3C1 | |
| SCHEMBL21361280 | 0.72 | PNMT (0.41) | HTR2AHTR2CHTR2BMAOAMAOB | |
| SCHEMBL20892518 | 0.72 | MDM2 (0.36) | HTR2AHTR2CHTR2BADRA2A | |
| SCHEMBL23102828 | 0.71 | IMPDH2 (0.61) | SLC6A4MAOAHTR1DMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230265173-A1 | SULFONAMIDE-CONTAINING LINKAGE SYSTEMS FOR DRUG CONJUGATES | ZYMEWORKS BC INC. (CA) | 2023-08-24 | — | — | US | disclosed |
| US-9918473-B2 | Use of aryl carbamates in agriculture and other plant-related areas | North Carolian State University (US) | 2018-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230265173-A1 | SULFONAMIDE-CONTAINING LINKAGE SYSTEMS FOR DRUG CONJUGATES | MPST, TPST2, SULT1A1 | SLC6A2 413/4885SLC6A4 747/4885CYP2D6 639/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.