Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 15/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 14/20 | 0.40 |
| ▸ | HPGD | P15428 | 8/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 6/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19980841 | 0.70 | CCNA2 (0.39) | ALDH1A1SMN1; SMN2KDM4EHPGDLMNA | |
| SCHEMBL19980892 | 0.67 | CTSK (0.42) | POLBALDH1A1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL242891 | 0.66 | TSHR (0.51) | POLBALDH1A1TDP1 | |
| SCHEMBL1798323 | 0.66 | TSHR (0.58) | POLBALDH1A1HPGDTDP1 | |
| SCHEMBL8360577 | 0.65 | MCL1 (0.49) | POLBALDH1A1LMNATDP1MAPT | |
| SCHEMBL8748019 | 0.64 | TSHR (0.56) | POLBALDH1A1TDP1 | |
| SCHEMBL5846107 | 0.64 | TSHR (0.51) | POLBALDH1A1TDP1NPSR1KMT2A | |
| SCHEMBL107954 | 0.63 | TSHR (0.58) | POLBALDH1A1SMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL17142026 | 0.63 | TSHR (0.59) | POLBALDH1A1TDP1CYP3A4NPSR1 | |
| SCHEMBL11295972 | 0.62 | THRB (0.40) | POLBALDH1A1SMN1; SMN2L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601268-B1 | PARTICLES FOR ELECTROPHORETIC DISPLAYS | MERCK PATENT GMBH (DE) | 2018-03-21 | — | — | EP | disclosed |