Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 3/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.35 |
| ▸ | CDK2 | P24941 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.33 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.33 |
| ▸ | ITGAL | P20701 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983715 | 0.89 | HTR2A (0.42) | CHRNB2CHRNA7CHRNA4GPR84ADRB3 | |
| SCHEMBL19984030 | 0.86 | GPR84 (0.48) | CHRNB2CHRNA7CHRNA4GPR84HTR2A | |
| SCHEMBL19984001 | 0.84 | MAPK8 (0.48) | CHRNB2CHRNA7CHRNA4GPR84HTR2A | |
| SCHEMBL19983945 | 0.83 | TBXAS1 (0.41) | GPR84HTR2ASLC6A4KCNH2CDK2 | |
| SCHEMBL15897700 | 0.81 | CHRNB2 (0.72) | CHRNB2CHRNA7CHRNA4GPR84IDO1 | |
| SCHEMBL19983859 | 0.81 | CDK2 (0.41) | GPR84IDO1HTR2ASLC6A4KCNH2 | |
| SCHEMBL19984002 | 0.81 | CHRNB2 (0.51) | CHRNB2CHRNA7CHRNA4GPR84IDO1 | |
| SCHEMBL19984234 | 0.81 | BCL6 (0.38) | CHRNB2CHRNA7CHRNA4GPR84SLC6A4 | |
| SCHEMBL19984197 | 0.80 | GPR84 (0.49) | CHRNB2CHRNA7CHRNA4GPR84ADRB3 | |
| SCHEMBL19983894 | 0.79 | GPR84 (0.39) | CHRNB2CHRNA7CHRNA4GPR84HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |