Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.51 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 11/20 | 0.46 |
| ▸ | GOT1 | P17174 | 1/20 | 0.43 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.38 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984113 | 0.84 | KIF11 (0.41) | CHRNB2CHRNA7CHRNA4GPR84IDO1 | |
| SCHEMBL15897700 | 0.82 | CHRNB2 (0.72) | CHRNB2CHRNA7CHRNA4GPR84IDO1 | |
| SCHEMBL19984000 | 0.81 | HTR2A (0.46) | CHRNB2CHRNA7CHRNA4GPR84MEN1 | |
| SCHEMBL19983851 | 0.81 | CHRNB2 (0.47) | CHRNB2CHRNA7CHRNA4EGFRGPR84 | |
| SCHEMBL19983739 | 0.81 | CHRNB2 (0.50) | CHRNB2CHRNA7CHRNA4EGFRGPR84 | |
| SCHEMBL19984119 | 0.80 | GPR84 (0.53) | CHRNB2CHRNA7CHRNA4GPR84 | |
| SCHEMBL19984146 | 0.80 | CHRNB2 (0.46) | CHRNB2CHRNA7CHRNA4GPR84IDO1 | |
| SCHEMBL19984216 | 0.79 | GPR84 (0.48) | CHRNB2CHRNA7CHRNA4GPR84 | |
| SCHEMBL19983831 | 0.78 | HTR2A (0.49) | GPR84MEN1KMT2A | |
| SCHEMBL19984088 | 0.78 | HTR1D (0.50) | CHRNB2CHRNA7CHRNA4GPR84MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |