Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | FADS1 | O60427 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983847 | 0.89 | TBXAS1 (0.42) | TBXAS1CDK2HTR2ASLC6A4KCNH2 | |
| SCHEMBL19984128 | 0.88 | TBXAS1 (0.42) | TBXAS1CDK2HTR2ASLC6A4KCNH2 | |
| SCHEMBL19984030 | 0.85 | GPR84 (0.48) | HTR2ASLC6A4KCNH2GPR84HTR1A | |
| SCHEMBL19983845 | 0.85 | TBXAS1 (0.44) | TBXAS1CDK2HTR2ASLC6A4KCNH2 | |
| SCHEMBL19983859 | 0.84 | CDK2 (0.41) | CDK2HTR2ASLC6A4KCNH2TRPA1 | |
| SCHEMBL19983715 | 0.84 | HTR2A (0.42) | HTR2AKDM4EGPR84HTR1D | |
| SCHEMBL19983739 | 0.83 | CHRNB2 (0.50) | CDK2HTR2ASLC6A4KCNH2GPR84 | |
| SCHEMBL19983905 | 0.83 | GPR84 (0.45) | HTR2ASLC6A4KCNH2GPR84 | |
| SCHEMBL19983800 | 0.82 | GPR84 (0.36) | TBXAS1CDK2SLC6A4KCNH2TRPA1 | |
| SCHEMBL19984001 | 0.82 | MAPK8 (0.48) | HTR2ASLC6A4KDM4EGPR84HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |