Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | HTR6 | P50406 | 3/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983831 | 0.86 | HTR2A (0.49) | KMT2AHTR2AHTR6MEN1GPR84 | |
| SCHEMBL19983833 | 0.81 | SCN9A (0.44) | MMP2MMP9KMT2AHTR2AHTR1A | |
| SCHEMBL19984215 | 0.78 | GAA (0.47) | KMT2AHTR2AHTR6MEN1GPR84 | |
| SCHEMBL19984000 | 0.77 | HTR2A (0.46) | KMT2AHTR2AHTR1AMEN1GPR84 | |
| SCHEMBL19983830 | 0.77 | HTR2A (0.48) | KMT2AHTR2AHTR6HTR1AHTR7 | |
| SCHEMBL19984159 | 0.77 | SCN9A (0.36) | KMT2AHTR2AHTR6HTR1AMEN1 | |
| SCHEMBL19984242 | 0.76 | HTR2A (0.44) | KMT2AHTR2AHTR6HTR1AHTR7 | |
| SCHEMBL19984119 | 0.76 | GPR84 (0.53) | HTR2AHTR6HTR1AGPR84 | |
| SCHEMBL19984002 | 0.76 | CHRNB2 (0.51) | KMT2AMEN1GPR84 | |
| SCHEMBL19984180 | 0.75 | HTR2A (0.47) | HTR2AGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |