Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | GOT1 | P17174 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 2/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984134 | 0.92 | HTR2A (0.41) | CDK2MEN1KMT2ATRPV1LMNA | |
| SCHEMBL19983900 | 0.88 | CDK2 (0.42) | CDK2TRPV1GOT1TRPA1HTR6 | |
| SCHEMBL19983859 | 0.87 | CDK2 (0.41) | CDK2TRPV1HTR2AGOT1TRPA1 | |
| SCHEMBL19983959 | 0.82 | KMT2A (0.40) | CDK2MEN1KMT2ATRPV1SMN1; SMN2 | |
| SCHEMBL19983830 | 0.80 | HTR2A (0.48) | CDK2MEN1KMT2ASMN1; SMN2HTR2A | |
| SCHEMBL19984215 | 0.79 | GAA (0.47) | CDK2MEN1KMT2ASMN1; SMN2HTR2A | |
| SCHEMBL19983831 | 0.78 | HTR2A (0.49) | MEN1KMT2ALMNAMAPK1SMN1; SMN2 | |
| SCHEMBL19983934 | 0.78 | TUBB1 (0.41) | CDK2TRPV1IDO1TDO2 | |
| SCHEMBL19983858 | 0.75 | GPR84 (0.40) | HTR2AAPPGPR84 | |
| SCHEMBL19983951 | 0.75 | TRPV1 (0.41) | CDK2MEN1KMT2ATRPV1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |