Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.44 |
| ▸ | GOT1 | P17174 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | CDK2 | P24941 | 2/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 2/20 | 0.37 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984088 | 0.88 | HTR1D (0.50) | HTR1AHTR1DHTR1BCHRNB2CHRNA7 | |
| SCHEMBL19983847 | 0.87 | TBXAS1 (0.42) | TBXAS1GOT1HTR1AHTR1DHTR1B | |
| SCHEMBL19984128 | 0.86 | TBXAS1 (0.42) | TBXAS1GOT1HTR1AHTR1DHTR1B | |
| SCHEMBL19984119 | 0.85 | GPR84 (0.53) | HTR1ACHRNB2CHRNA7CHRNA4GPR84 | |
| SCHEMBL19983945 | 0.85 | TBXAS1 (0.41) | TBXAS1HTR1AHTR1DHTR1BGPR84 | |
| SCHEMBL19984000 | 0.84 | HTR2A (0.46) | HTR1AHTR1DCHRNB2CHRNA7CHRNA4 | |
| SCHEMBL19983749 | 0.81 | GPR84 (0.39) | TBXAS1HTR1AHTR1DHTR1BCHRNB2 | |
| SCHEMBL19983831 | 0.81 | HTR2A (0.49) | GPR84HTR6HTR2A | |
| SCHEMBL19983734 | 0.79 | GPR84 (0.46) | HTR1ACHRNB2CHRNA7CHRNA4GPR84 | |
| SCHEMBL19984216 | 0.79 | GPR84 (0.48) | HTR1AHTR1DHTR1BCHRNB2CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |