Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 10/20 | 0.37 |
| ▸ | MAP2K2 | P36507 | 2/20 | 0.35 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.32 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983939 | 0.83 | ABL1 (0.37) | KDRKCNH2 | |
| SCHEMBL19984191 | 0.82 | CYP3A4 (0.40) | KDRNAMPT | |
| SCHEMBL16619031 | 0.81 | HDAC1 (0.42) | DHODHMAP2K2MAP2K1NAMPT | |
| SCHEMBL19984127 | 0.71 | NUDT1 (0.36) | FLT1KDRKCNH2NUDT1 | |
| SCHEMBL16618817 | 0.71 | HDAC1 (0.41) | DHODHNAMPT | |
| SCHEMBL16618614 | 0.71 | FBP1 (0.42) | NUDT1NAMPT | |
| SCHEMBL19983721 | 0.70 | HTR2C (0.32) | NAMPT | |
| SCHEMBL19983844 | 0.70 | ALDH1A1 (0.35) | MAPK14NAMPT | |
| SCHEMBL16618671 | 0.69 | HDAC1 (0.41) | NAMPT | |
| SCHEMBL19983916 | 0.69 | KDM4E (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |