Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 6/20 | 0.37 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 2/20 | 0.35 |
| ▸ | MAT2A | P31153 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16618694 | 0.83 | LMNA (0.40) | ABL1KDRP2RX7NPC1RAB9A | |
| SCHEMBL19983961 | 0.83 | DHODH (0.37) | KDRKCNH2 | |
| SCHEMBL19984191 | 0.81 | CYP3A4 (0.40) | KDRKITGPBAR1 | |
| SCHEMBL16619188 | 0.75 | LMNA (0.40) | ABL1KDRNPC1RAB9A | |
| SCHEMBL19984007 | 0.74 | MAT2A (0.34) | ABL1KDRP2RX7NPC1RAB9A | |
| SCHEMBL16618640 | 0.74 | LMNA (0.41) | ABL1KDR | |
| SCHEMBL19984203 | 0.73 | ABL1 (0.35) | ABL1KDRP2RX7NPC1RAB9A | |
| SCHEMBL17971588 | 0.73 | LMNA (0.42) | — | |
| SCHEMBL19983965 | 0.72 | LRRK2 (0.33) | ABL1 | |
| SCHEMBL19984154 | 0.69 | P2RX7 (0.34) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |