Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984299 | 0.89 | SLC6A4 (0.35) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 | |
| SCHEMBL19983825 | 0.82 | CARM1 (0.32) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL16618625 | 0.81 | PDE4A (0.40) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL19984212 | 0.79 | SLC6A4 (0.33) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 | |
| SCHEMBL16619072 | 0.76 | RORC (0.41) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL16618589 | 0.70 | HTR6 (0.44) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL19984279 | 0.69 | SLC6A4 (0.35) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 | |
| SCHEMBL16626620 | 0.67 | SLC6A2 (0.43) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL16619014 | 0.67 | HTR6 (0.37) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL19983775 | 0.67 | EGFR (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |