Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 4/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | VDR | P11473 | 2/20 | 0.31 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.30 |
| ▸ | YAP1 | P46937 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984029 | 0.91 | APP (0.35) | SLC6A4HTR2AKCNH2LMNAMAPK1 | |
| SCHEMBL19983946 | 0.86 | SLC6A4 (0.38) | SLC6A4SLC6A2SLC6A3HTR2AKCNH2 | |
| SCHEMBL19984163 | 0.84 | FADS1 (0.36) | SLC6A4SLC6A2SLC6A3HTR2AKCNH2 | |
| SCHEMBL19983775 | 0.83 | EGFR (0.34) | VDR | |
| SCHEMBL19984021 | 0.81 | GAK (0.40) | SLC6A4HTR2AKCNH2 | |
| SCHEMBL16626550 | 0.81 | HTR6 (0.41) | MAPK1TEAD1YAP1 | |
| SCHEMBL19983954 | 0.81 | HTR2A (0.32) | SLC6A4HTR2AKCNH2 | |
| Hydrochloric Acid SCHEMBL16619304 | 0.81 | HTR6 (0.40) | MAPK1TEAD1YAP1 | |
| SCHEMBL19983933 | 0.78 | KDM4E (0.32) | — | |
| SCHEMBL19983888 | 0.77 | P2RX7 (0.31) | SLC6A4SLC6A2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |