Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 7/20 | 0.35 |
| ▸ | HTR2A | P28223 | 4/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | YWHAH | Q04917 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983977 | 0.89 | SLC6A4 (0.32) | SLC6A4HTR2AKCNH2POLBSLC6A2 | |
| SCHEMBL19983825 | 0.82 | CARM1 (0.32) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL19984212 | 0.80 | SLC6A4 (0.33) | SLC6A4HTR2AKCNH2TP53SLC6A2 | |
| SCHEMBL16618589 | 0.80 | HTR6 (0.44) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL19984040 | 0.75 | MTNR1A (0.34) | SLC6A4HTR2AKCNH2MEN1KMT2A | |
| SCHEMBL16618630 | 0.74 | HTR6 (0.45) | SLC6A4SLC6A2SLC6A3MAPT | |
| SCHEMBL19984031 | 0.72 | ALDH1A1 (0.38) | POLBMAPT | |
| SCHEMBL19983978 | 0.72 | MTNR1A (0.35) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 | |
| SCHEMBL19984279 | 0.70 | SLC6A4 (0.35) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 | |
| SCHEMBL16618625 | 0.70 | PDE4A (0.40) | SLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |