Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.34 |
| ▸ | ERBB3 | P21860 | 2/20 | 0.34 |
| ▸ | ERBB4 | Q15303 | 2/20 | 0.34 |
| ▸ | FBP1 | P09467 | 2/20 | 0.33 |
| ▸ | BRAF | P15056 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | CTSC | P53634 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | VDR | P11473 | 1/20 | 0.31 |
| ▸ | CFD | P00746 | 1/20 | 0.31 |
| ▸ | KIT | P10721 | 1/20 | 0.30 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983885 | 0.91 | FBP1 (0.39) | EGFRERBB2ERBB3ERBB4FBP1 | |
| SCHEMBL19984029 | 0.88 | APP (0.35) | EGFRBRAF | |
| SCHEMBL19984182 | 0.86 | P2RX7 (0.31) | P2RX7 | |
| SCHEMBL19984250 | 0.85 | HTR2A (0.30) | — | |
| SCHEMBL19983825 | 0.85 | CARM1 (0.32) | — | |
| SCHEMBL19984154 | 0.84 | P2RX7 (0.34) | P2RX7 | |
| SCHEMBL19983777 | 0.84 | ADRB2 (0.37) | FBP1P2RX7 | |
| SCHEMBL19984021 | 0.84 | GAK (0.40) | EGFRERBB2ERBB3ERBB4 | |
| SCHEMBL19984279 | 0.83 | SLC6A4 (0.35) | VDR | |
| SCHEMBL19983946 | 0.82 | SLC6A4 (0.38) | FBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |