Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 6/20 | 0.33 |
| ▸ | BCR | P11274 | 3/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 2/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.31 |
| ▸ | SYK | P43405 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983844 | 0.91 | ALDH1A1 (0.35) | KITCYP11B1CYP11B2 | |
| SCHEMBL19984203 | 0.91 | ABL1 (0.35) | MAT2AABL1BCRKDRKIT | |
| SCHEMBL19983777 | 0.86 | ADRB2 (0.37) | TRPA1NPC1RAB9AP2RX7 | |
| SCHEMBL19984127 | 0.86 | NUDT1 (0.36) | MAT2AKDRCYP11B1CYP11B2CYP2C9 | |
| SCHEMBL19983721 | 0.86 | HTR2C (0.32) | ROCK2 | |
| SCHEMBL19983812 | 0.85 | CYP11B1 (0.38) | MAT2AABL1BCRCYP11B1CYP11B2 | |
| SCHEMBL19984009 | 0.85 | ALPL (0.37) | KDRCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL19983981 | 0.84 | CNR2 (0.34) | KDRCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL19983879 | 0.83 | — | — | |
| SCHEMBL19983874 | 0.82 | CYP19A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |