Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.41 |
| ▸ | GOT1 | P17174 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MPO | P05164 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984189 | 0.88 | BRD4 (0.38) | TRPV1GOT1SLC6A4CDK2HTR2A | |
| SCHEMBL19984218 | 0.87 | SLC6A4 (0.39) | TRPV1GOT1SLC6A4CDK2HTR2A | |
| SCHEMBL19983959 | 0.86 | KMT2A (0.40) | TRPV1CDK2HTR2AGPR84MEN1 | |
| SCHEMBL19984035 | 0.80 | HTR2A (0.47) | HTR2ACHRNB2CHRNA7CHRNA4GPR84 | |
| SCHEMBL19983900 | 0.77 | CDK2 (0.42) | TRPV1GOT1CDK2HTR6 | |
| SCHEMBL3843653 | 0.76 | HAT1 (0.44) | TRPV1 | |
| SCHEMBL19983859 | 0.76 | CDK2 (0.41) | TRPV1GOT1SLC6A4CDK2HTR2A | |
| SCHEMBL19984222 | 0.75 | CDK2 (0.41) | TRPV1GOT1CDK2HTR2AGPR84 | |
| SCHEMBL19984036 | 0.73 | LMNA (0.44) | SLC6A4HTR2ACHRNB2CHRNA7CHRNA4 | |
| SCHEMBL19983786 | 0.73 | SLC6A4 (0.43) | SLC6A4CDK2HTR2ACHRNB2CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |