Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | BUB1 | O43683 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984132 | 0.90 | HDAC11 (0.31) | METAP2 | |
| SCHEMBL19983981 | 0.88 | CNR2 (0.34) | BUB1 | |
| SCHEMBL19983856 | 0.88 | GRM4 (0.34) | METAP2TRPV1 | |
| SCHEMBL19983721 | 0.85 | HTR2C (0.32) | METAP2 | |
| SCHEMBL19984177 | 0.83 | HTR2C (0.39) | METAP2 | |
| SCHEMBL19983883 | 0.83 | HTR2C (0.32) | — | |
| SCHEMBL19983826 | 0.82 | ABCG2 (0.37) | METAP2 | |
| SCHEMBL19983848 | 0.82 | MAP3K8 (0.32) | METAP2 | |
| SCHEMBL19984007 | 0.82 | MAT2A (0.34) | — | |
| SCHEMBL19984127 | 0.82 | NUDT1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |