Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.36 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.35 |
| ▸ | GOT1 | P17174 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984218 | 0.88 | SLC6A4 (0.39) | BRD4CDK2TRPV1GOT1CHRNB2 | |
| SCHEMBL19983951 | 0.88 | TRPV1 (0.41) | CDK2TRPV1GOT1CHRNB2CHRNA7 | |
| SCHEMBL19983959 | 0.87 | KMT2A (0.40) | BRD4CDK2TRPV1HTR2AHTR6 | |
| SCHEMBL19983900 | 0.81 | CDK2 (0.42) | CDK2TRPV1GOT1HTR1AHTR7 | |
| SCHEMBL13579085 | 0.78 | HTR2A (0.46) | HTR2ASLC6A4 | |
| SCHEMBL19983801 | 0.77 | GPR84 (0.41) | CHRNB2CHRNA7CHRNA4HTR2AHTR1A | |
| SCHEMBL19984023 | 0.75 | HTR2A (0.47) | CHRNB2CHRNA7CHRNA4HTR2AHTR1A | |
| SCHEMBL19983859 | 0.74 | CDK2 (0.41) | CDK2TRPV1GOT1HTR2AHTR6 | |
| SCHEMBL19983786 | 0.73 | SLC6A4 (0.43) | CDK2CHRNB2CHRNA7CHRNA4HTR2A | |
| SCHEMBL19983967 | 0.73 | GPR84 (0.47) | CHRNB2CHRNA7CHRNA4HTR2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |