Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | APLNR | P35414 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984189 | 0.87 | BRD4 (0.38) | KMT2AMEN1TRPV1HTR2AKDM4E | |
| SCHEMBL19984218 | 0.86 | SLC6A4 (0.39) | TRPV1HTR2ACDK2GPR84BRD4 | |
| SCHEMBL19983951 | 0.86 | TRPV1 (0.41) | KMT2AMEN1TRPV1HTR2AKDM4E | |
| SCHEMBL19984222 | 0.82 | CDK2 (0.41) | KMT2AMEN1TRPV1HTR2ASMN1; SMN2 | |
| SCHEMBL14017704 | 0.79 | APLNR (0.54) | KMT2AMEN1HTR2AAPLNR | |
| SCHEMBL19984134 | 0.76 | HTR2A (0.41) | KMT2AMEN1TRPV1HTR2ASMN1; SMN2 | |
| SCHEMBL19983900 | 0.73 | CDK2 (0.42) | TRPV1HTR6CDK2 | |
| SCHEMBL19983859 | 0.72 | CDK2 (0.41) | TRPV1HTR2AHTR6CDK2GPR84 | |
| SCHEMBL19983967 | 0.72 | GPR84 (0.47) | HTR2AGPR84 | |
| SCHEMBL19983786 | 0.72 | SLC6A4 (0.43) | HTR2ACDK2GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |