Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | GOT1 | P17174 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.35 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 3/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983859 | 0.89 | CDK2 (0.41) | CDK2GOT1TRPA1IDO1TDO2 | |
| SCHEMBL19984222 | 0.88 | CDK2 (0.41) | CDK2GOT1TRPA1IDO1TDO2 | |
| SCHEMBL19984215 | 0.87 | GAA (0.47) | CDK2HTR6GAA | |
| SCHEMBL19983847 | 0.85 | TBXAS1 (0.42) | CDK2GOT1TRPA1TRPV1HTR1A | |
| SCHEMBL19984134 | 0.84 | HTR2A (0.41) | CDK2TRPV1HTR6HTR1A | |
| SCHEMBL19983891 | 0.82 | GPR84 (0.49) | HTR6HTR1A | |
| SCHEMBL19984005 | 0.82 | HTR2A (0.44) | — | |
| SCHEMBL19984189 | 0.81 | BRD4 (0.38) | CDK2GOT1TRPV1HTR6HTR1A | |
| SCHEMBL19983867 | 0.80 | HTR2C (0.42) | HTR6HTR1AGAA | |
| SCHEMBL19984197 | 0.80 | GPR84 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |