Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.38 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.37 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | TTK | P33981 | 2/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983947 | 0.81 | TUBB1 (0.48) | TUBB1MAPTALDH1A1L3MBTL1NR4A2 | |
| SCHEMBL19984222 | 0.78 | CDK2 (0.41) | CDK2IDO1TDO2TRPV1 | |
| SCHEMBL19983834 | 0.74 | PRKAG1 (0.42) | TUBB1MAPTNR4A2ROCK2ROCK1 | |
| SCHEMBL19984304 | 0.74 | NR4A2 (0.38) | TUBB1IDO1TDO2STING1NR4A2 | |
| SCHEMBL19984228 | 0.72 | NR4A2 (0.46) | NR4A2 | |
| SCHEMBL16618640 | 0.71 | LMNA (0.41) | CYP2C9CYP2C19 | |
| SCHEMBL19983975 | 0.70 | ALK (0.40) | NR4A2 | |
| SCHEMBL19984134 | 0.70 | HTR2A (0.41) | CDK2MAPTTRPV1 | |
| SCHEMBL17417643 | 0.69 | ALDH1A1 (0.52) | TUBB1CDK2MAPTALDH1A1ROCK2 | |
| SCHEMBL31375074 | 0.69 | ALDH1A1 (0.52) | TUBB1CDK2MAPTALDH1A1ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |