Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 7/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16626787 | 0.81 | HTR6 (0.40) | ALDH1A1RAB9AMAPTCYP1A2CYP2C9 | |
| Hydrochloric Acid SCHEMBL16618771 | 0.80 | HTR6 (0.39) | ALDH1A1RAB9AMAPTCYP1A2CYP2C9 | |
| SCHEMBL19984236 | 0.77 | SLC6A4 (0.46) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 | |
| SCHEMBL19984162 | 0.75 | PRMT6 (0.40) | ALDH1A1CYP1A2CYP2C9CYP2D6LMNA | |
| SCHEMBL19984210 | 0.75 | PRMT6 (0.40) | ALDH1A1CYP1A2CYP2C9CYP2D6LMNA | |
| SCHEMBL19984177 | 0.74 | HTR2C (0.39) | ALDH1A1KMT2ALTA4H | |
| SCHEMBL19983736 | 0.73 | MAPT (0.38) | ALDH1A1MAPTCYP1A2CYP2C9MEN1 | |
| SCHEMBL16626641 | 0.72 | POLB (0.38) | MAPTSLC6A4HTR2APOLBKCNH2 | |
| SCHEMBL19984196 | 0.72 | PRMT6 (0.36) | CYP2C9MEN1CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL16618961 | 0.71 | POLB (0.38) | MAPTSLC6A4HTR2APOLBKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |