Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | BCL6 | P41182 | 2/20 | 0.38 |
| ▸ | BCOR | Q6W2J9 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983733 | 0.88 | SLC6A2 (0.37) | MAPTCYP2C19CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL19984171 | 0.86 | POLB (0.37) | BCL6ALDH1A1KDM4E | |
| SCHEMBL19983883 | 0.86 | HTR2C (0.32) | BCL6BCOR | |
| SCHEMBL19983850 | 0.85 | LRRK2 (0.40) | BCL6ABCG2 | |
| SCHEMBL19984135 | 0.83 | BCL6 (0.40) | MAPTBCL6BCORALDH1A1KDM4E | |
| SCHEMBL19983743 | 0.83 | SRC (0.40) | GAA | |
| SCHEMBL16626687 | 0.82 | MAPT (0.38) | MAPTCYP2C19CYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL16618902 | 0.81 | MAPT (0.37) | MAPTCYP2C19CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL19984127 | 0.81 | NUDT1 (0.36) | CYP2C19CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL19984087 | 0.81 | SLC6A2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |