Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 13/20 | 0.46 |
| ▸ | HTR2A | P28223 | 11/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 11/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.33 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16626656 | 0.82 | SLC6A4 (0.46) | SLC6A4HTR2AKCNH2MRGPRX4SLC6A2 | |
| Hydrochloric Acid SCHEMBL16619083 | 0.81 | SLC6A4 (0.45) | SLC6A4HTR2AKCNH2MRGPRX4SLC6A2 | |
| SCHEMBL19984295 | 0.77 | ALDH1A1 (0.36) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 | |
| SCHEMBL19983743 | 0.74 | SRC (0.40) | SLC6A4SLC6A2 | |
| SCHEMBL19983981 | 0.74 | CNR2 (0.34) | — | |
| SCHEMBL19983812 | 0.73 | CYP11B1 (0.38) | — | |
| SCHEMBL19983883 | 0.73 | HTR2C (0.32) | SLC6A4SLC6A2EGFR | |
| SCHEMBL19984087 | 0.73 | SLC6A2 (0.34) | SLC6A4SLC6A2EGFR | |
| SCHEMBL19984203 | 0.72 | ABL1 (0.35) | — | |
| SCHEMBL19983856 | 0.72 | GRM4 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |