Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984823 | 0.86 | ADAMTS4 (0.55) | PPARDNPC1RAB9AKDM4EMAPT | |
| SCHEMBL19984825 | 0.82 | ADAMTS4 (0.57) | PPARDNPC1RAB9AKDM4EMAPT | |
| SCHEMBL19984976 | 0.79 | APLNR (0.54) | PPARDMAPTKMT2AHPGDGAA | |
| SCHEMBL19984967 | 0.79 | ADAMTS4 (0.54) | PPARDNPC1RAB9AKDM4EMAPT | |
| SCHEMBL12171886 | 0.78 | PPARD (0.56) | PPARDHSD17B10NPC1RAB9AKDM4E | |
| SCHEMBL19984971 | 0.76 | ADAMTS4 (0.45) | PPARDNPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL19984985 | 0.76 | ADAMTS4 (0.55) | HPGDGAA | |
| SCHEMBL2435361 | 0.74 | PPARD (0.50) | PPARDHSD17B10NPC1RAB9AKDM4E | |
| SCHEMBL12171732 | 0.71 | NPC1 (0.66) | PPARDNPC1RAB9AKDM4EMAPT | |
| SCHEMBL11615095 | 0.70 | ALDH1A1 (0.58) | HSD17B10NPC1RAB9AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018051255-A1 | CYCLIC SUBSTITUTED-1,3,4-OXADIAZOLE AND THIADIAZOLE COMPOUNDS AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2018-03-22 | — | — | WO | disclosed |