Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 8/20 | 0.54 |
| ▸ | PPARD | Q03181 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.46 |
| ▸ | GRK2 | P25098 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984789 | 0.84 | APLNR (0.54) | APLNRPARP1HPGDKMT2A | |
| SCHEMBL19984985 | 0.83 | ADAMTS4 (0.55) | APLNRPARP1GAAHPGD | |
| SCHEMBL19984846 | 0.79 | PPARD (0.49) | PPARDGAAHPGDKMT2AMAPK1 | |
| SCHEMBL12171886 | 0.78 | PPARD (0.56) | PPARDHPGDKMT2AMAPT | |
| SCHEMBL16495669 | 0.77 | WNT3A (0.46) | APLNRKMT2AROCK2MAPTROCK1 | |
| SCHEMBL19984823 | 0.76 | ADAMTS4 (0.55) | PPARDHPGDKMT2AMAPK1MAPT | |
| SCHEMBL2440740 | 0.76 | HPGD (0.52) | APLNRPPARDHPGDKMT2AMAPK1 | |
| SCHEMBL19984815 | 0.74 | KMT2A (0.48) | APLNRHPGDKMT2AMAPK1 | |
| SCHEMBL19984977 | 0.73 | APLNR (0.44) | APLNRPARP1HPGDKMT2AMAPK1 | |
| SCHEMBL15595972 | 0.73 | SMN1; SMN2 (0.52) | KMT2AMAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018051255-A1 | CYCLIC SUBSTITUTED-1,3,4-OXADIAZOLE AND THIADIAZOLE COMPOUNDS AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2018-03-22 | — | — | WO | disclosed |