Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984932 | 0.86 | NFE2L2 (0.36) | NFE2L2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL19984944 | 0.84 | NFE2L2 (0.38) | NFE2L2L3MBTL1ALDH1A1MAPT | |
| SCHEMBL21538744 | 0.82 | NFE2L2 (0.34) | NFE2L2ALDH1A1GAAMAPTKDM4E | |
| SCHEMBL21538695 | 0.80 | ADRA2A (0.43) | L3MBTL1TSHRADRA2AADRA2BADRA2C | |
| SCHEMBL21538751 | 0.79 | NFE2L2 (0.37) | NFE2L2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL21538770 | 0.79 | NFE2L2 (0.37) | NFE2L2L3MBTL1GAAMEN1KMT2A | |
| SCHEMBL19985052 | 0.79 | NFE2L2 (0.35) | NFE2L2L3MBTL1TSHRALDH1A1GAA | |
| SCHEMBL21538717 | 0.78 | NFE2L2 (0.36) | NFE2L2ALDH1A1GAAKMT2AMAPT | |
| SCHEMBL21538696 | 0.78 | NFE2L2 (0.38) | NFE2L2L3MBTL1GAAMAPTKDM4E | |
| SCHEMBL21538699 | 0.76 | L3MBTL1 (0.36) | NFE2L2L3MBTL1TSHRALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512843-B1 | PLANT GROWTH REGULATOR COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-10-20 | — | — | EP | disclosed |
| US-11136292-B2 | Plant growth regulator compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2021-10-05 | — | — | US | disclosed |
| US-20190330148-A1 | PLANT GROWTH REGULATOR COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-10-31 | — | — | US | disclosed |
| WO-2018050477-A1 | PLANT GROWTH REGULATOR COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11136292-B2 | Plant growth regulator compounds | FGF1, MST1, CDC20 | NFE2L2 2365/4885L3MBTL1 3472/4885TSHR 455/4885 |
| US-20190330148-A1 | PLANT GROWTH REGULATOR COMPOUNDS | FGF1, MST1, CDC20 | NFE2L2 2365/4885L3MBTL1 3472/4885TSHR 455/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.