SCHEMBL19985035

SCHEMBL19985035

CCOC(=O)/C(=C/OC1OC(=O)C(C)=C1C)C1CCOc2ccccc21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.34
AMY1A P0DUB6 1/20 0.34
GAA P10253 1/20 0.34
SI P14410 1/20 0.34
MGAM2 Q2M2H8 1/20 0.34
PTGDR2 Q9Y5Y4 3/20 0.34
TSHR P16473 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
NPSR1 Q6W5P4 1/20 0.33
SSTR4 P31391 1/20 0.33
ALDH1A1 P00352 3/20 0.33
MAPT P10636 3/20 0.33
MAPK1 P28482 1/20 0.33
POLB P06746 3/20 0.33
MEN1 O00255 3/20 0.32
KMT2A Q03164 3/20 0.32
LMNA P02545 2/20 0.31
PLIN1 O60240 1/20 0.31
PLIN5 Q00G26 1/20 0.31
ABHD5 Q8WTS1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19984934 0.90 TSHR (0.36) MGAMAMY1AGAASIMGAM2
SCHEMBL23877361 0.88 PTGDR2 (0.34) PTGDR2SSTR4
SCHEMBL19984922 0.84 PIN1 (0.37) L3MBTL1ALDH1A1MAPTPOLB
SCHEMBL19985052 0.83 NFE2L2 (0.35) MGAMAMY1AGAASIMGAM2
SCHEMBL21538720 0.83 ANO1 (0.37) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL19985043 0.83 HPGD (0.36) ALDH1A1MEN1KMT2AKDM4E
SCHEMBL21538772 0.81 SIGMAR1 (0.33) TSHRL3MBTL1ALDH1A1MAPTMAPK1
SCHEMBL21538716 0.81 FFAR1 (0.35) MGAMAMY1AGAASIMGAM2
SCHEMBL19985049 0.80 MEN1 (0.40) MGAMAMY1AGAASIMGAM2
SCHEMBL23877355 0.78 GLS (0.33) SSTR4ALDH1A1MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3512843-B1 PLANT GROWTH REGULATOR COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2021-10-20 EP disclosed
US-11136292-B2 Plant growth regulator compounds SYNGENTA PARTICIPATIONS AG (CH) 2021-10-05 US disclosed
US-20190330148-A1 PLANT GROWTH REGULATOR COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2019-10-31 US disclosed
WO-2018050477-A1 PLANT GROWTH REGULATOR COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2018-03-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11136292-B2 Plant growth regulator compounds FGF1, MST1, CDC20 MGAM 1637/4885AMY1A 3375/4885GAA 1330/4885
US-20190330148-A1 PLANT GROWTH REGULATOR COMPOUNDS FGF1, MST1, CDC20 MGAM 1637/4885AMY1A 3375/4885GAA 1330/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.