Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MIF | P14174 | 1/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.48 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.48 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.48 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diphenylamine SCHEMBL28258923 | 0.88 | ALDH1A1 (0.69) | ALDH1A1HSD17B10ALOX15CYP2C9NR1I2 | |
| SCHEMBL26373519 | 0.83 | ALDH1A1 (0.53) | ALDH1A1HSD17B10ALOX15CYP2C9LMNA | |
| SCHEMBL10366243 | 0.81 | ALDH1A1 (0.50) | ALDH1A1HSD17B10ALOX15CYP2C9TYR | |
| SCHEMBL26114037 | 0.79 | MAPT (0.48) | ALDH1A1HSD17B10ALOX15CYP2C9LMNA | |
| SCHEMBL8060147 | 0.77 | NR1H4 (0.60) | ALDH1A1HSD17B10ALOX15CYP2C9NR1I2 | |
| SCHEMBL19985758 | 0.77 | HPGD (0.46) | ALDH1A1HSD17B10ALOX15CYP2C9NR1I2 | |
| SCHEMBL4530935 | 0.77 | CYP3A4 (0.59) | ALDH1A1HSD17B10ALOX15CYP2C9LMNA | |
| SCHEMBL11371987 | 0.76 | HPGD (0.54) | ALDH1A1HSD17B10ALOX15LMNAL3MBTL1 | |
| SCHEMBL19985671 | 0.75 | RAPGEF4 (0.54) | ALDH1A1HSD17B10ALOX15CYP2C9NR1I2 | |
| SCHEMBL4099452 | 0.73 | CFTR (0.46) | ALDH1A1HSD17B10ALOX15CYP2C9NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3516019-B1 | LUBRICANT COMPOSITIONS STABILIZED BY MIXTURES OF DIARYLAMINE AND HYDROXYDIARYLAMINE ANTIOXIDANTS | LANXESS CORP (US) | 2023-06-14 | — | — | EP | disclosed |
| EP-3516020-B1 | ALKYLATED 3-HYDROXYDIPHENYLAMINE ANTIOXIDANTS | LANXESS CORP (US) | 2022-05-25 | — | — | EP | disclosed |
| US-10723969-B2 | Lubricant compositions stabilized by mixtures of diarylamine and hydroxydiarylamine antioxidants | LANXESS SOLUTIONS US INC. (US) | 2020-07-28 | — | — | US | disclosed |
| US-10563145-B2 | Alkylated 3-hydroxydiphenylamine antioxidants | LANXESS SOLUTIONS US INC. (US) | 2020-02-18 | — | — | US | disclosed |
| WO-2018057364-A1 | LUBRICANT COMPOSITIONS STABILIZED BY MIXTURES OF DIARYLAMINE AND HYDROXYDIARYLAMINE ANTIOXIDANTS | LANXESS SOLUTIONS US INC. (US) | 2018-03-29 | — | — | WO | disclosed |
| WO-2018057366-A1 | ALKYLATED 3-HYDROXYDIPHENYLAMINE ANTIOXIDANTS | LANXESS SOLUTIONS US INC. (US) | 2018-03-29 | — | — | WO | disclosed |
| US-20180079985-A1 | ALKYLATED 3-HYDROXYDIPHENYLAMINE ANTIOXIDANTS | LANXESS SOLUTIONS US INC. | 2018-03-22 | — | — | US | disclosed |
| US-20180079987-A1 | LUBRICANT COMPOSITIONS STABILIZED BY MIXTURES OF DIARYLAMINE AND HYDROXYDIARYLAMINE ANTIOXIDANTS | LANXESS SOLUTIONS US INC. | 2018-03-22 | — | — | US | disclosed |
| US-20180079985-A1 | ALKYLATED 3-HYDROXYDIPHENYLAMINE ANTIOXIDANTS | LANXESS SOLUTIONS US INC. | 2018-03-22 | — | — | US | disclosed |
| US-20180079987-A1 | LUBRICANT COMPOSITIONS STABILIZED BY MIXTURES OF DIARYLAMINE AND HYDROXYDIARYLAMINE ANTIOXIDANTS | LANXESS SOLUTIONS US INC. | 2018-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180079985-A1 | ALKYLATED 3-HYDROXYDIPHENYLAMINE ANTIOXIDANTS | GPX4, GSTO1, LPO | ALDH1A1 129/4885HSD17B10 92/4885ALOX15 81/4885 |
| US-10563145-B2 | Alkylated 3-hydroxydiphenylamine antioxidants | GPX4, GSTO1, LPO | ALDH1A1 129/4885HSD17B10 92/4885ALOX15 81/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.