Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19985846 | 0.80 | CYP4F2 (0.32) | CYP4F2CYP4A11 | |
| SCHEMBL19985864 | 0.79 | F2 (0.41) | CYP4F2CYP4A11MAPT | |
| SCHEMBL19972236 | 0.72 | SMN1; SMN2 (0.40) | MAPT | |
| SCHEMBL12611715 | 0.67 | NLRP3 (0.37) | MAPT | |
| SCHEMBL16585893 | 0.66 | KMT2A (0.41) | MAPT | |
| SCHEMBL29021038 | 0.65 | GAA (0.40) | MAPT | |
| SCHEMBL28296997 | 0.63 | SMN1; SMN2 (0.40) | MAPT | |
| SCHEMBL3499415 | 0.63 | CYP4F2 (0.56) | CYP4F2CYP4A11 | |
| SCHEMBL6576846 | 0.63 | SMN1; SMN2 (0.44) | MAPT | |
| SCHEMBL19985848 | 0.63 | MAPT (0.55) | MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180078541-A1 | 6-MEMBERED CYCLIC AMINES OR LACTAMES SUBSTITUTED WITH UREA AND PHENYL | Grünenthal GmbH (DE) | 2018-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180078541-A1 | 6-MEMBERED CYCLIC AMINES OR LACTAMES SUBSTITUTED WITH UREA AND PHENYL | FPR2, FPR1, FPR3 | CYP4F2 525/4885CYP4A11 1298/4885MAPT 4276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.