Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19985859 | 0.86 | HPGD (0.51) | ALDH1A1TSHRHPGDTDP1LMNA | |
| SCHEMBL19985847 | 0.84 | DPP4 (0.45) | ALDH1A1TSHRHPGDMAPK1TDP1 | |
| SCHEMBL19972419 | 0.76 | PDE4A (0.52) | ALDH1A1TSHRHPGDSMN1; SMN2PDE4A | |
| SCHEMBL19972374 | 0.76 | PDE4A (0.52) | ALDH1A1TSHRHPGDSMN1; SMN2PDE4A | |
| SCHEMBL19972421 | 0.76 | PDE4A (0.52) | ALDH1A1TSHRHPGDSMN1; SMN2PDE4A | |
| SCHEMBL19985852 | 0.76 | ALDH1A1 (0.50) | ALDH1A1MAPK1LMNASMN1; SMN2KMT2A | |
| SCHEMBL19985866 | 0.75 | KMT2A (0.46) | ALDH1A1TSHRHPGDMAPK1TDP1 | |
| SCHEMBL19985863 | 0.75 | KMT2A (0.46) | ALDH1A1TSHRHPGDMAPK1TDP1 | |
| SCHEMBL7247095 | 0.74 | HTT (0.60) | ALDH1A1TSHRHPGDLMNASMN1; SMN2 | |
| SCHEMBL7247085 | 0.74 | HTT (0.60) | ALDH1A1TSHRHPGDLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180078541-A1 | 6-MEMBERED CYCLIC AMINES OR LACTAMES SUBSTITUTED WITH UREA AND PHENYL | Grünenthal GmbH (DE) | 2018-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180078541-A1 | 6-MEMBERED CYCLIC AMINES OR LACTAMES SUBSTITUTED WITH UREA AND PHENYL | FPR2, FPR1, FPR3 | ALDH1A1 3156/4885TSHR 1909/4885HPGD 104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.