Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | HTT | P42858 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | IDH1 | O75874 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28574430 | 0.94 | NAMPT (0.47) | MEN1KMT2AHTTLMNAMAPT | |
| SCHEMBL19986720 | 0.90 | RAB9A (0.49) | MEN1KMT2AHTTLMNAMAPT | |
| SCHEMBL19986465 | 0.85 | PRMT3 (0.38) | MEN1KMT2ALMNAMAPTRAB9A | |
| SCHEMBL19986531 | 0.85 | MEN1 (0.44) | MEN1KMT2ALMNAMAPTNPC1 | |
| SCHEMBL19986618 | 0.85 | MEN1 (0.38) | MEN1KMT2AHTTLMNAMAPT | |
| SCHEMBL19986553 | 0.83 | KMT2A (0.63) | MEN1KMT2AHTTLMNAMAPT | |
| SCHEMBL19986463 | 0.81 | LMNA (0.60) | MEN1KMT2AHTTLMNAMAPT | |
| SCHEMBL19986502 | 0.81 | KMT2A (0.60) | MEN1KMT2AHTTLMNAMAPT | |
| SCHEMBL19986510 | 0.80 | LMNA (0.65) | MEN1KMT2AHTTLMNAMAPT | |
| SCHEMBL19986539 | 0.78 | LMNA (0.58) | MEN1KMT2AHTTLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050110-A1 | NOVEL CAPSID PROTEIN ASSEMBLY INHIBITOR | 正大天晴药业集团股份有限公司 | 2018-03-22 | — | — | WO | disclosed |