Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.35 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19986531 | 0.92 | MEN1 (0.44) | MEN1KMT2AP2RX7LMNAMAPT | |
| SCHEMBL19986465 | 0.85 | PRMT3 (0.38) | MEN1KMT2AP2RX7LMNAMAPT | |
| SCHEMBL19986512 | 0.85 | MEN1 (0.54) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL28574430 | 0.85 | NAMPT (0.47) | MEN1KMT2ALMNAMAPTHTT | |
| SCHEMBL19986624 | 0.81 | LMNA (0.40) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL19986705 | 0.81 | MARS1 (0.47) | MEN1KMT2ALMNAALDH1A1HTT | |
| SCHEMBL19986720 | 0.81 | RAB9A (0.49) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL19986691 | 0.80 | LMNA (0.45) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL19986619 | 0.79 | NAMPT (0.37) | KMT2ALMNAMAPTFGFR3KDR | |
| SCHEMBL19986466 | 0.73 | L3MBTL1 (0.36) | FGFR3KDRRAB9ACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050110-A1 | NOVEL CAPSID PROTEIN ASSEMBLY INHIBITOR | 正大天晴药业集团股份有限公司 | 2018-03-22 | — | — | WO | disclosed |