Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CCNC | P24863 | 1/20 | 0.45 |
| ▸ | CDK8 | P49336 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | CASR | P41180 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19986715 | 0.85 | KMT2A (0.41) | KDM4ENAMPTMAPTMEN1KMT2A | |
| SCHEMBL19986692 | 0.81 | NAMPT (0.38) | RAB9AKDM4ENAMPTMAPTMEN1 | |
| SCHEMBL19986721 | 0.79 | RAB9A (0.45) | RAB9AKDM4ECCNCCDK8NAMPT | |
| SCHEMBL19986611 | 0.78 | LMNA (0.50) | RAB9AALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL19986510 | 0.75 | LMNA (0.65) | RAB9AKDM4ETSHRALDH1A1MAPT | |
| SCHEMBL19986509 | 0.74 | BLM (0.43) | RAB9AKDM4ECCNCCDK8NAMPT | |
| SCHEMBL19986446 | 0.72 | KMT2A (0.49) | RAB9AKDM4ENAMPTALDH1A1MAPT | |
| SCHEMBL19986554 | 0.72 | MEN1 (0.47) | NAMPTRECQLALDH1A1MAPTMEN1 | |
| SCHEMBL19986717 | 0.72 | MEN1 (0.44) | RAB9AALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL26463986 | 0.70 | ALDH1A1 (0.62) | RAB9ACCNCCDK8NAMPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050110-A1 | NOVEL CAPSID PROTEIN ASSEMBLY INHIBITOR | 正大天晴药业集团股份有限公司 | 2018-03-22 | — | — | WO | disclosed |