Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CCR3 | P51677 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19986715 | 0.93 | KMT2A (0.41) | NAMPTKMT2APOLBMAPTKDM4E | |
| SCHEMBL19986708 | 0.83 | KDM4E (0.39) | NAMPTSCN10AKMT2AHDAC3HDAC1 | |
| SCHEMBL19986612 | 0.81 | RAB9A (0.45) | NAMPTLMNAKMT2APOLBMAPT | |
| SCHEMBL19986619 | 0.81 | NAMPT (0.37) | NAMPTSCN10ALMNAKMT2AHDAC3 | |
| SCHEMBL19986691 | 0.80 | LMNA (0.45) | LMNAKMT2AMAPTCCR3RAB9A | |
| SCHEMBL19986717 | 0.73 | MEN1 (0.44) | LMNAKMT2AMAPTCCR3RAB9A | |
| SCHEMBL19986510 | 0.71 | LMNA (0.65) | LMNAKMT2AMAPTKDM4ENPC1 | |
| SCHEMBL19986507 | 0.70 | KMT2A (0.38) | NAMPTKMT2AMAPTKDM4EMEN1 | |
| SCHEMBL19986699 | 0.70 | LMNA (0.53) | NAMPTLMNAKMT2APOLBMAPT | |
| SCHEMBL19986611 | 0.69 | LMNA (0.50) | LMNAKMT2APOLBMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050110-A1 | NOVEL CAPSID PROTEIN ASSEMBLY INHIBITOR | 正大天晴药业集团股份有限公司 | 2018-03-22 | — | — | WO | disclosed |