Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 14/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 6/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18572585 | 0.85 | AHCY (0.52) | NNMTPRMT5WDR77 | |
| SCHEMBL9109736 | 0.85 | AHCY (0.52) | NNMTPRMT5WDR77 | |
| SCHEMBL22002025 | 0.85 | AHCY (0.52) | NNMTPRMT5WDR77 | |
| SCHEMBL9469927 | 0.84 | NNMT (0.42) | NNMTPRMT5WDR77 | |
| SCHEMBL29540101 | 0.82 | NNMT (0.43) | NNMTPRMT5WDR77 | |
| SCHEMBL22509889 | 0.82 | NNMT (0.43) | NNMTPRMT5WDR77 | |
| SCHEMBL22509958 | 0.81 | PRMT5 (0.41) | NNMTPRMT5WDR77 | |
| SCHEMBL18589317 | 0.80 | UBA6 (0.41) | NNMTPRMT5WDR77 | |
| SCHEMBL1947419 | 0.80 | UBA6 (0.41) | NNMTPRMT5WDR77 | |
| SCHEMBL936138 | 0.80 | UBA6 (0.41) | NNMTPRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180086785-A1 | SUBSTITUTED PYRROLO[2,3-D]PYRIMIDINES | MILLENNIUM PHARMACEUTICALS, INC. | 2018-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180086785-A1 | SUBSTITUTED PYRROLO[2,3-D]PYRIMIDINES | TYMP, TYMS, PPA1 | NNMT 299/4885PRMT5 544/4885WDR77 1195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.