Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | PTPRA | P18433 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19996574 | 0.87 | PPARA (0.42) | ALDH1A1MAPK1PPARGPPARAL3MBTL1 | |
| SCHEMBL19996566 | 0.86 | PRMT5 (0.42) | ALDH1A1TSHRMAPK1PPARGPPARA | |
| SCHEMBL19996568 | 0.85 | KMT2A (0.48) | ALDH1A1TSHRMAPK1PPARGPPARA | |
| SCHEMBL23964465 | 0.84 | KMT2A (0.42) | ADRB2ADRB1ADRB3TLR2CDC25B | |
| SCHEMBL19996558 | 0.82 | PPARG (0.38) | ALDH1A1MAPK1PPARGPPARAL3MBTL1 | |
| SCHEMBL19996579 | 0.82 | KDM4E (0.45) | ALDH1A1TSHRCYP1A2MAPK1ADRB2 | |
| SCHEMBL19996584 | 0.80 | LPAR1 (0.39) | ALDH1A1TSHRMAPK1L3MBTL1CASP3 | |
| SCHEMBL25761318 | 0.78 | TSHR (0.44) | ALDH1A1TSHRCYP1A2MAPK1L3MBTL1 | |
| SCHEMBL19996583 | 0.78 | CA1 (0.51) | ALDH1A1MAPK1L3MBTL1LPAR1ADRB2 | |
| SCHEMBL24180469 | 0.78 | CA1 (0.51) | ALDH1A1MAPK1L3MBTL1LPAR1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230173406-A1 | CHROMATOGRAPHIC COLUMNS AND SEPARATION DEVICES COMPRISING A SUPERFICIALLY POROUS MATERIAL; AND USE THEREOF FOR SUPERCRITICAL FLUID CHROMATOGRAPHY AND OTHER CHROMATOGRAPHY | WATERS TECHNOLOGIES CORPORATION (US) | 2023-06-08 | — | — | US | disclosed |
| US-11577179-B2 | Chromatographic columns and separation devices comprising a superficially porous material; and use thereof for supercritical fluid chromatography and other chromatography | WATERS TECHNOLOGIES CORPORATION (US) | 2023-02-14 | — | — | US | disclosed |
| EP-3936226-A2 | CHROMATOGRAPHIC COLUMNS AND SEPARATION DEVICES COMPRISING A SUPERFICIALLY POROUS MATERIAL; AND USE THEREOF FOR SUPERCRITICAL FLUID CHROMATOGRAPHY AND OTHER CHROMATOGRAPHY | Waters Technologies Corporation (US) | 2022-01-12 | — | — | EP | disclosed |
| US-20210331138-A1 | CHROMATOGRAPHIC MATERIALS | WATERS TECHNOLOGIES CORPORATION (US) | 2021-10-28 | — | — | US | disclosed |
| US-11059026-B2 | Chromatographic materials | WATERS TECHNOLOGIES CORPORATION (US) | 2021-07-13 | — | — | US | disclosed |
| US-20190217273-A1 | CHROMATOGRAPHIC MATERIALS | WATERS TECHNOLOGIES CORPORATION (US) | 2019-07-18 | — | — | US | disclosed |
| US-10265679-B2 | Chromatographic materials | WATERS TECHNOLOGIES CORPORATION (US) | 2019-04-23 | — | — | US | disclosed |
| US-20190092800-A1 | LIQUID CHROMATOGRAPHIC SEPARATION OF CARBOHYDRATE TAUTOMERS | WATERS TECHNOLOGIES CORPORATION | 2019-03-28 | — | — | US | disclosed |
| US-9925521-B2 | Chromatographic materials | WATERS TECHNOLOGIES CORPORATION (US) | 2018-03-27 | — | — | US | disclosed |
| US-9925521-B2 | Chromatographic materials | WATERS TECHNOLOGIES CORPORATION (US) | 2018-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190092800-A1 | LIQUID CHROMATOGRAPHIC SEPARATION OF CARBOHYDRATE TAUTOMERS | GALE, MGAM, ALDOA | ALDH1A1 2963/4885TSHR 3591/4885CYP1A2 1860/4885 |
| US-20190217273-A1 | CHROMATOGRAPHIC MATERIALS | HAX1, CXCR1, YBX1 | ALDH1A1 1836/4885TSHR 2500/4885CYP1A2 1833/4885 |
| US-20230173406-A1 | CHROMATOGRAPHIC COLUMNS AND SEPARATION DEVICES COMPRISING A SUPERFICIALLY POROUS MATERIAL; AND USE THEREOF FOR SUPERCRITICAL FLUID CHROMATOGRAPHY AND OTHER CHROMATOGRAPHY | SPECC1L, CCL5, CCR5 | ALDH1A1 3401/4885TSHR 4745/4885CYP1A2 3279/4885 |
| US-11577179-B2 | Chromatographic columns and separation devices comprising a superficially porous material; and use thereof for supercritical fluid chromatography and other chromatography | SEPTIN9, PORCN, SPECC1L | ALDH1A1 3766/4885TSHR 4592/4885CYP1A2 3834/4885 |
| US-11059026-B2 | Chromatographic materials | HAX1, CXCR1, YBX1 | ALDH1A1 1836/4885TSHR 2500/4885CYP1A2 1833/4885 |
| US-20210331138-A1 | CHROMATOGRAPHIC MATERIALS | HAX1, CXCR1, YBX1 | ALDH1A1 1836/4885TSHR 2500/4885CYP1A2 1833/4885 |
| US-10265679-B2 | Chromatographic materials | HAX1, CXCR1, YBX1 | ALDH1A1 1836/4885TSHR 2500/4885CYP1A2 1833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.