Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 6/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19996574 | 0.90 | PPARA (0.42) | LMNATDP1ADRB2ADRB1ADRB3 | |
| SCHEMBL23964627 | 0.86 | LMNA (0.46) | KMT2ALMNATDP1CHRNA7TBXAS1 | |
| SCHEMBL19996567 | 0.84 | ALDH1A1 (0.41) | KMT2ATLR2ADRB2ADRB1ADRB3 | |
| SCHEMBL19996556 | 0.82 | ACHE (0.44) | KMT2ALMNATDP1CHRNA7ADRB2 | |
| SCHEMBL19996568 | 0.78 | KMT2A (0.48) | KMT2ALMNAADRB2ADRB1ADRB3 | |
| SCHEMBL23964466 | 0.78 | L3MBTL1 (0.40) | KMT2ATDP1KDM4EPRMT5WDR77 | |
| SCHEMBL24180469 | 0.78 | CA1 (0.51) | TDP1ADRB2ADRB1ADRB3CDC25B | |
| SCHEMBL19996583 | 0.78 | CA1 (0.51) | TDP1ADRB2ADRB1ADRB3CDC25B | |
| SCHEMBL19996576 | 0.77 | ALDH1A1 (0.46) | KMT2ALMNATDP1ADRB2ADRB1 | |
| SCHEMBL20224969 | 0.74 | TBXAS1 (0.60) | KMT2ALMNATDP1CHRNA7TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210331138-A1 | CHROMATOGRAPHIC MATERIALS | WATERS TECHNOLOGIES CORPORATION (US) | 2021-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210331138-A1 | CHROMATOGRAPHIC MATERIALS | HAX1, CXCR1, YBX1 | KMT2A 2972/4885LMNA 647/4885TDP1 3439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.