Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 17/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20002964 | 0.87 | RORC (0.35) | RORCKDM1A | |
| SCHEMBL20003037 | 0.86 | RORC (0.38) | RORCMAPK1 | |
| SCHEMBL20002167 | 0.85 | KDM1A (0.40) | RORCKDM1A | |
| SCHEMBL20002280 | 0.85 | TACR1 (0.40) | RORC | |
| SCHEMBL20003049 | 0.82 | AKR1C3 (0.51) | — | |
| SCHEMBL20002669 | 0.82 | NOTUM (0.45) | RORC | |
| SCHEMBL20002969 | 0.82 | NOTUM (0.45) | RORC | |
| SCHEMBL20002664 | 0.81 | TSHR (0.41) | MAPK1 | |
| SCHEMBL20002631 | 0.81 | HSD11B1 (0.33) | RORC | |
| SCHEMBL20002352 | 0.81 | MAPT (0.39) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3092229-B1 | PYRROLIDINYL SULFONE DERIVATIVES AND THEIR USE AS ROR GAMMA MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2018-03-28 | — | — | EP | disclosed |