SCHEMBL20004548

SCHEMBL20004548

CCCCOc1cc(C)c(C#Cc2ccc(C)cc2)c(F)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 2/20 0.40
DRD4 P21917 2/20 0.40
DRD3 P35462 2/20 0.40
KDM4E B2RXH2 1/20 0.39
GAA P10253 1/20 0.39
HPGD P15428 1/20 0.39
ACACB O00763 8/20 0.38
MAPT P10636 2/20 0.36
THRB P10828 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
MITF O75030 1/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
LTA4H P09960 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
KCNH2 Q12809 1/20 0.35
CHRNB2 P17787 1/20 0.35
CHRNB4 P30926 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20004622 0.85 MCHR1 (0.40) ACACBMAPTTHRBL3MBTL1
SCHEMBL14887180 0.81 LTA4H (0.40) ACACBLTA4HCHRNB2CHRNB4CHRNA3
SCHEMBL19999352 0.80 ACACB (0.40) ACACBMAPTALDH1A1MEN1KMT2A
SCHEMBL20005218 0.80 RARA (0.36) KDM4EGAAHPGDACACBL3MBTL1
SCHEMBL19999557 0.80 ACACB (0.42) DRD2DRD4DRD3ACACBALDH1A1
SCHEMBL20004842 0.80 RARB (0.36) KDM4EGAAHPGDACACB
SCHEMBL20005203 0.79 ACACB (0.45) ACACBLMNASMN1; SMN2
SCHEMBL20004754 0.79 ACACB (0.40) KDM4EACACBSMN1; SMN2
SCHEMBL20004573 0.79 MCHR1 (0.39) ACACBMAPTALDH1A1LMNAKMT2A
SCHEMBL20004766 0.78 MAPT (0.39) GAAACACBMAPTALDH1A1CHRNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3299439-A1 LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC Corporation (JP) 2018-03-28 EP disclosed